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PWT-33597 free base

CAT: 0931-T211812-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211812-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1246203-32-6
Target
PI3K, Apoptosis, mTOR
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling
Bioactivity
PWT-33597 (VDC-597) free base is a dual inhibitor of PI3Kα and mTOR that effectively obstructs downstream signaling pathways of PI3K and mTOR. This compound induces apoptosis in tumor cells and inhibits tumor growth. PWT-33597 free base demonstrates antitumor activity and can be used in research related to renal cell carcinoma and other tumors.
Smiles
O=S(=O)(NC=1C=CC(=CC1)C=2N=C(N=C(N2)N3CCOCC3)N4C(=NC=5C(OC)=CC=CC54)C(F)F)CCN(C)C
Molecular Formula
C26H30F2N8O4S
Molecular Weight
588.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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