Auristatin S

CAT: 0931-MF-0118618-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0118618-01Size:10 mg
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CAS Number
3028453-70-2
Target
Others|||Microtubule Associated
Related Pathways
Cytoskeletal Signaling|||Others
Bioactivity
AuristatinS is a potent anti-tumor agent that serves as an Auristatin payload. It effectively reduces the bystander effect and decreases off-target toxicity. In the Karpas/KarpasBVR cell model, AuristatinS exhibits excellent tolerability. It can be used as the cytotoxic component in antibody-drug conjugates (ADCs) for treating various types of cancer.
Smiles
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)CO)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C)C)CO)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Molecular Formula
C38H65N5O8
Molecular Weight
719.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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