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Monomethyl auristatin E

CAT: 0931-T6897-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T6897-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
474645-27-7
Target
Apoptosis, ADC Cytotoxin, Microtubule Associated
Related Pathways
Apoptosis, Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
Purity
0.999
Bioactivity
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.
Smiles
CC[C@H](C)C([C@@H](CC(=O)N1CCC[C@H]1C(OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)[C@@H](C(C)C)C(=O)NC(=O)[C@@H](NC)C(C)C
Molecular Formula
C39H67N5O7
Molecular Weight
717.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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