Auristatin E

• Target :

  ADC Cytotoxin|||Microtubule Associated

• Related Pathways :

  Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

• Purity :

  0.9881

• Bioactivity :

  Auristatin E, a cytotoxic tubulin modifier, disrupts cell division by inhibiting tubulin polymerisation. This compound demonstrates potent and selective antitumor activities, serving as an MMAE analog and cytotoxin in antibody-drug conjugates.

• Smiles :

  [H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1

• Molecular Formula :

  C40H69N5O7

• Molecular Weight :

  732.01

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  160800-57-7