Auristatin E

CAT: 0931-T14348-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T14348-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

160800-57-7

Target

ADC Cytotoxin, Microtubule Associated

Related Pathways

Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related

Purity

0.9881

Bioactivity

Auristatin E, a cytotoxic tubulin modifier, disrupts cell division by inhibiting tubulin polymerisation. This compound demonstrates potent and selective antitumor activities, serving as an MMAE analog and cytotoxin in antibody-drug conjugates.

Smiles

[H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1

Molecular Formula

C40H69N5O7

Molecular Weight

732.01

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
MBS3845699-01	Auristatin E
OR1024019-01	Auristatin F
HY-164107	Auristatin S

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