PPAR? agonist 19

• Target:

  PPAR|||COX

• Related Pathways:

  Neuroscience|||DNA Damage/DNA Repair|||Immunology/Inflammation|||Metabolism

• Bioactivity:

  PPAR? agonist19 (Compound 5e) is a PPAR? agonist with an IC50 of 11.27 ?M for COX-1 and 0.05 ?M for COX-2. It enhances glucose uptake in rat hemidiaphragm assays more effectively than pioglitazone. Additionally, PPAR? agonist19 reduces hyperglycemia and insulin resistance in type 2 diabetic rat models and protects against renal and lipid damage caused by metabolic dysfunction.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C