STING agonist-43

• Target:

  STING

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 ?M. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.

• Smiles:

  O=C(OCC)CN1C2=CC=C(C=C2C(=O)C3=CC(OC)=C(C(=C31)C)C)C

• Molecular Formula:

  C21H23NO4

• Molecular Weight:

  353.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2882097-31-4