LSD1-IN-43

• Target:

  Beta Amyloid|||Histone Demethylase

• Related Pathways:

  Neuroscience|||Chromatin/Epigenetic

• Bioactivity:

  LSD1-IN-43 is a highly selective, reversible, and orally active LSD1 inhibitor with blood-brain barrier permeability, showing an IC50 value of 0.8 ?M. It exhibits lower inhibitory activity against LSD1 homologs MAO-A and MAO-B. LSD1-IN-43 significantly inhibits A? aggregation and enhances neuronal cell viability induced by A?. It is applicable in Alzheimer's disease (AD) research.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C