LSD1-IN-20

• Target:

  Histone Demethylase|||Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9957

• Bioactivity:

  Lsd1-in-20 is a potent dual inhibitor of LSD1/G9a with Ki values of 0.44 and 0.68 ?M, respectively. LSD1-IN-20 showed antiproliferative activity against THP-1 leukemia cells and MDA-MB-231 breast cancer cells in vitro, with IC50 of 0.51 and 1.60 ?M, respectively, at 72 h.

• Smiles:

  N(C=1C2=C(N=C(NCCCN(C)C)N1)C=C(OC)C(OC)=C2)C3CCN(CC4=CC=CC=C4)CC3

• Molecular Formula:

  C27H38N6O2

• Molecular Weight:

  478.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1239589-91-3