LSD1-IN-20

CAT: 0931-MF-0050360-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0050360-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1239589-91-3
Target
Histone Demethylase|||Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9957
Bioactivity
Lsd1-in-20 is a potent dual inhibitor of LSD1/G9a with Ki values of 0.44 and 0.68 ?M, respectively. LSD1-IN-20 showed antiproliferative activity against THP-1 leukemia cells and MDA-MB-231 breast cancer cells in vitro, with IC50 of 0.51 and 1.60 ?M, respectively, at 72 h.
Smiles
N(C=1C2=C(N=C(NCCCN(C)C)N1)C=C(OC)C(OC)=C2)C3CCN(CC4=CC=CC=C4)CC3
Molecular Formula
C27H38N6O2
Molecular Weight
478.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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