Products for Research Use Only
RegisterLogin

LRRK2-IN-19

CAT: 0931-T210737-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T210737-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2839667-09-1
Target
Ligands for Target Protein for PROTAC, LRRK2
Related Pathways
PROTAC, Autophagy
Bioactivity
LRRK2-IN-19 is a PROTAC-targeted protein ligand utilized in the synthesis of PROTAC JH-XII-03-02. JH-XII-03-02 acts as an effective and selective LRRK2 PROTAC degrader, which is applicable for research in Parkinson's disease.
Smiles
N1=CN=C(C=C1C2=NNC=3C=CC(OC4(C)CC4)=CC23)N5CCNCC5
Molecular Formula
C19H22N6O
Molecular Weight
350.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

5-(1-methylcyclopropyl)oxy-3-(6-piperazin-1-ylpyrimidin-4-yl)-1H-indazole
CAS Number2839667-09-1
PubChem CID90398228
IUPAC Name5-(1-methylcyclopropyl)oxy-3-(6-piperazin-1-ylpyrimidin-4-yl)-1H-indazole
Molecular FormulaC19H22N6O
Molecular Weight350.4
XLogP2
Topological Polar Surface Area79
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count26
Formal Charge0
Complexity494
SMILES
CC1(CC1)OC2=CC3=C(C=C2)NN=C3C4=CC(=NC=N4)N5CCNCC5
InChI
InChI=1S/C19H22N6O/c1-19(4-5-19)26-13-2-3-15-14(10-13)18(24-23-15)16-11-17(22-12-21-16)25-8-6-20-7-9-25/h2-3,10-12,20H,4-9H2,1H3,(H,23,24)
InChIKey
SYTCTBFQLWTHFY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-(1-methylcyclopropyl)oxy-3-(6-piperazin-1-ylpyrimidin-4-yl)-1H-indazole
CAS: 2839667-09-1
CID: 90398228
Formula: C19H22N6O
MW: 350.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight350.4
XLogP32
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass350.18550935
Monoisotopic Mass350.18550935
Topological Polar Surface Area79 Ų
Heavy Atom Count26
Formal Charge0
Complexity494
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T204380-01LRRK2-IN-16
T2246-01LRRK2-IN-1
T63620-01LRRK2-IN-3
T63057-01LRRK2-IN-5
T86825-01LRRK2-IN-14
T212497-01LRRK2-IN-20
T200475-01LRRK2-IN-15
T86823-01LRRK2-IN-12
T62871-01LRRK2-IN-6
T79746-01LRRK2-IN-10

Alternative Products

CatalogName
GTR19263248-01LRRK2-IN-19
CSB-CL722493HULRRK2
ASE-9403Genome-Edited iPSCs (LRRK2 Knockout, LRRK2-/-)
GTR17691822Phospho-LRRK2/LRRK2 Rabbit Monoclonal Antibody
BA3691-5LRRK2-IN-7
A3558-5.1LRRK2-IN-1
HY-145318LRRK2-IN-3
HY-168041LRRK2-IN-15
HY-169576LRRK2-IN-16
567645-01LRRK2 (FITC)

Popular Products