LRRK2-IN-3

• Target:

  Others|||LRRK2

• Related Pathways:

  Autophagy|||Others

• Bioactivity:

  LRRK2-IN-3 is a potent, selective, orally active LRRK2 inhibitor that crosses the blood-brain barrier with an IC50 value of 0.6 nM in hPBMCs. LRRK2-IN-3 can be used to study Parkinson's disease.

• Smiles:

  FC1(F)[C@@H](C1)N2C(C)=C(NC3=NC4=C(C=N3)C=C(Cl)C(=C4)C5CCN(CC5)[C@@]6(C)[C@@H](O)COC6)C=N2

• Molecular Formula:

  C25H29ClF2N6O2

• Molecular Weight:

  518.99

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2641054-60-4