Products for Research Use Only

LRRK2-IN-6

CAT: 0931-T62871-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62871-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, LRRK2
Related Pathways
Others, Autophagy
Bioactivity
LRRK2-IN-6 (compound 22) is an orally active, selective leucine-rich repeat protein kinase 2 (LRRK2) inhibitor with blood-brain barrier permeability, inhibiting GS LRRK2 (IC50: 4.6 μM) and WT LRRK2 (IC50: 49 μM) . LRRK2-IN-6 exhibited inhibitory effects on the autophosphorylation of LRRK2 at Ser1292 and Ser925.
Molecular Formula
C23H24F2N4O2S
Molecular Weight
458.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C