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LRRK2-IN-12

CAT: 0931-T86823-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86823-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3032733-05-1
Target
LRRK2
Related Pathways
Autophagy
Bioactivity
LRRK2-IN-12 (compound 1) is a potent inhibitor of LRRK2 (G20195) with an IC 50 of 0.45 nM, LRRK2 WT with an IC 50 of 1.1 nM, and LRRK2 WT ADP-Glo with an IC 50 of 0.46 nM. This compound is utilized in research related to Alzheimer's Disease [1].
Smiles
ClC=1C2=C3N(N1)CCCOC=4C(N=C(N3)N=C2)=C(C)N(N4)C5=C(OC)N=CC=C5
Molecular Formula
C18H17ClN8O2
Molecular Weight
412.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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