KRAS-IN-43

CAT: 0931-MF-0117914-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0117914-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ras
Related Pathways
MAPK
Bioactivity
KRAS-IN-43 (Compound 9) is a broad-spectrum KRAS inhibitor with IC50 values of 0.15 ?M for KRASG12V, 0.14 ?M for KRASG12C, and 0.47 ?M for wild-type KRAS. It disrupts the interaction between KRAS and cRAF and suppresses ERK phosphorylation. KRAS-IN-43 shows potential for research in KRAS mutation-associated cancers, including pancreatic, colorectal, and lung cancers.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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