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KRAS-IN-43

CAT: 0013-GTR19263193-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263193-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRAS-IN-43 (Compound 9) is a broad-spectrum KRAS inhibitor with IC50 values of 0.15 μM for KRASG12V, 0.14 μM for KRASG12C, and 0.47 μM for wild-type KRAS. It disrupts the interaction between KRAS and cRAF and suppresses ERK phosphorylation. KRAS-IN-43 shows potential for research in KRAS mutation-associated cancers, including pancreatic, colorectal, and lung cancers.
Field of Research
Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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