KRAS IN-44

CAT: 0931-T210689-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T210689-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

PDE, PI3K, Akt, Apoptosis, Ras, mTOR

Related Pathways

Cytoskeletal Signaling, MAPK, PI3K/Akt/mTOR signaling, Metabolism, Apoptosis

Bioactivity

KRAS IN-44 (Compound S2C2M2) is a PDE6D degrader. It inhibits PDE6D-dependent KRAS transport and downstream signaling pathways. Additionally, KRAS IN-44 downregulates EGF-induced phosphorylation of PI3K, AKT, and mTOR. It promotes apoptosis and exhibits antitumor activity against hepatoblastoma.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T79626-01	HCV-IN-44
T210360-01	HDAC6-IN-44
T209807-01	HPK1-IN-44
T208341-01	α-Glucosidase-IN-44
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HY-174379	KRAS IN-44
HY-142946	KRAS G12C inhibitor 44
JH18094	44'44'
abx302384-01	GTPase KRas (KRAS) Antibody
566703-01	KRAS
abx105485-01	GTPase KRas (KRAS) Antibody (Biotin)
abx600131-01	Human Gtpase Kras (KRAS) Protein
CSB-EP012493HU-01	Recombinant Human GTPase KRas (KRAS)
MBS962596-01	Recombinant Rat GTPase KRas (Kras)

KRAS IN-44

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