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KRAS inhibitor-13

CAT: 0931-T63164-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63164-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2230873-96-6
Target
Ras, Kras, Others
Related Pathways
GPCR/G Protein, MAPK, Others
Bioactivity
KRAS inhibitor-13 (compound 5-6) is a potent inhibitor of KRAS G12C (IC50: 0.883 μM) and demonstrates a p-ERK inhibitory effect in MIA PaCA-2 and A549 cells with IC50 values of 5.9 μM and >100 μM respectively. KRAS inhibitor-13 has potential applications in pancreatic, colorectal, and lung cancer studies.
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C(C=C)(=O)N1[C@@]2([C@@](N(C2)C3=C4C(=NS3)C(F)=C(C(Cl)=C4)C=5C6=C(C=C(O)C5)C=CC=C6)(CC1)[H])[H]
Molecular Formula
C25H19ClFN3O2S
Molecular Weight
479.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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HY-146543KRAS inhibitor-13
HY-143607KRAS G12D inhibitor 13
MBS3603444KRAS-G12C inhibitor 13
GTR19206013-01KRAS G12C inhibitor 13
A19041-100KRAS G12C inhibitor 13 100mg
A19041-10KRAS G12C inhibitor 13 10mg
A19041-5KRAS G12C inhibitor 13 5mg
A19041-1KRAS G12C inhibitor 13 1mg
A19041-50KRAS G12C inhibitor 13 50mg
A19041-25KRAS G12C inhibitor 13 25mg

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