Products for Research Use Only

VEGFR-2-IN-47

CAT: 0931-T210040-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210040-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
VEGFR-2-IN-47 (compound 7g) is a potent VEGFR-2 inhibitor with an IC50 of 0.072 μM. It induces G2/M phase cell cycle arrest and promotes apoptosis in MCF-7 cells, enhancing immune modulation by decreasing TNF-α levels and increasing IL-2 levels. VEGFR-2-IN-47 shows potential for research in breast cancer and liver cancer.
Molecular Formula
C23H22N6O4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C