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VEGFR-2-IN-78

CAT: 0804-HY-179046Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179046Size:1 Each
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Description
VEGFR-2-IN-78 (Compound 6b) is a potent VEGFR-2 inhibitor with an IC50 of 0.21 μM. VEGFR-2-IN-78 exhibits selective cytotoxicity against A-498 and MDA-MB-231 cells. VEGFR-2-IN-78 has antioxidant activity. VEGFR-2-IN-78 can be used in anti-angiogenesis research[1].
UNSPSC
12352005
Target
VEGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CC1=C(C(N/N=C/C2=CC=CC=C2)=O)S/C(N1C3=CC=CC=C3)=N/C4=NC5=CC=CC=C5S4
Molecular Formula
C25H19N5OS2
Molecular Weight
469.58
References & Citations
[1]Mohamed FAAA, et al. Design, synthesis, and computational validation of novel benzothiazole derivatives as dual anticancer-antioxidant agents targeting VEGFR-2. Bioorg Chem. 2025 Oct 15;166:109066.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1

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