Products for Research Use Only

HPK1-IN-43

CAT: 0931-T209490-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209490-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
IFNAR, MAPK, Interleukin
Related Pathways
Immunology/Inflammation, MAPK
Bioactivity
HPK1-IN-43 (compound 9f) is an HPK1 kinase inhibitor with an IC50 value of 0.32 nM. It inhibits the phosphorylation of the downstream protein SLP-76 in PBMC cells and enhances the secretion of interleukin 2 (IL-2) and interferon-γ (IFN-γ) . HPK1-IN-43 is applicable to cancer research.
Molecular Formula
C26H25F3N6O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C