PRO-905

CAT: 0931-MF-0116004-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0116004-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2762209-68-5
Target
Others
Related Pathways
Others
Bioactivity
Pro-905 is a phosphonate peptide with antitumor activity. It delivers the active nucleotide antimetabolite thioinosine monophosphate (TGMP) to tumors. Pro-905 effectively inhibits the binding of purine residue substrates to nucleic acids, thereby suppressing colony formation of human malignant peripheral nerve sheath tumor (MPNST) cells. It prevents purine residues from incorporating into nucleic acids, hindering cell growth. Additionally, Pro-905 inhibits the growth of MPNST and enhances the antitumor effect of JHU395.
Smiles
S=C1C2=C(N(C=N2)[C@@H]3O[C@H](COP(OC4=CC=CC=C4)(N[C@H](C(OC(C)C)=O)C)=O)[C@@H](O)[C@H]3O)NC(N)=N1
Molecular Formula
C22H29N6O8PS
Molecular Weight
568.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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