CPI-905

• Description:

  CPI-905 is a potent, selective, and cell-active EZH2 inhibitor[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H312-H332

• Target:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cpi-905.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(OC)=C(OCCO2)C2=C1)NCC3=C(C)C=C(C)NC3=O

• Molecular Formula:

  C18H20N2O5

• Molecular Weight:

  344.36

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations:

  [1]William D Bradley, et al. EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation. Chem Biol. 2014 Nov 20;21 (11) :1463-75.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [931078-17-0]