CPI-905

• Description :

  CPI-905 is a potent, selective, and cell-active EZH2 inhibitor[1].

• CAS Number :

  [931078-17-0]

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H312-H332

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cpi-905.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC(OC)=C(OCCO2)C2=C1)NCC3=C(C)C=C(C)NC3=O

• Molecular Formula :

  C18H20N2O5

• Molecular Weight :

  344.36

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations :

  [1]William D Bradley, et al. EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation. Chem Biol. 2014 Nov 20;21 (11) :1463-75.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported