PRO-905

CAT: 0804-HY-155995Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155995Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Pro-905 is a phosphite peptide with antitumor activity. Pro-905 delivers the active nucleotide antimetabolite thioguanosine monophosphate (TGMP) to the tumor. Pro-905 effectively prevents incorporation of purine salvage substrates into nucleic acids and inhibits colony formation in human malignant peripheral nerve sheath tumors (MPNST) cells. Pro-905 inhibits purine salvage incorporation to nucleic acids and prevents cell growth. Pro-905 inhibits the growth of MPNST and enhances the anti-tumor efficacy of JHU395 (HY-124778) [1].
CAS Number
[2762209-68-5]
Product Name Alternative
MK-905
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pro-905.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=S)=C3N=C2)O[C@@H]1COP(N[C@H](C(OC(C)C)=O)C)(OC4=CC=CC=C4)=O
Molecular Formula
C22H29N6O8PS
Molecular Weight
568.54
References & Citations
[1]Lemberg KM, et al. Pro-905, a novel purine antimetabolite, combines with glutamine amidotransferase inhibition to suppress growth of malignant peripheral nerve sheath tumor. Mol Cancer Ther. 2023 Aug 24:MCT-23-0258.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-117787TUG-905
HY-111085CPI-905
HY-P3727Lys-Pro-Pro-Thr-Pro-Pro-Pro-Glu-Pro-Glu-Thr
HY-P4495H-Pro-Pro-Pro-OH
HY-115820Cyclo (Pro-Pro)
HY-P4612-01Z-Pro-Pro
HY-P4365D-Pro-Pro-Glu
HY-134454-01Z-Pro-Pro-CHO
HY-W041990-01Fmoc-Pro-Pro-OH
HY-114424H-Ile-Pro-Pro-OH

Alternative Products

CatalogName
MF-0116004-01PRO-905
MBS5786012BMS-905
7745/5CST 905
MF-0137924-01TUG-905
MBS5776795CPI-905
MBS859917-01Ret (Ab-905) Antibody
BHSP-905Handheld Spectrophotometer BHSP-905
BMET-905Gloss Meter BMET-905
BJR-905Ultrasonic Cleaner (BJR-905)
BHBD-905Manual Wheelchair BHBD-905

Popular Products