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Cbl-b-IN-15

CAT: 0013-GTR19261321-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261321-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cbl-b-IN-15 (compound 25) is an inhibitor of the RING finger E3 ubiquitin ligase Cbl, demonstrating an IC50 of 15 nM. Cbl-b refers to Casitas B-lineage Lymphoma proto-oncogene-b, which can inhibit the activation of T cells, natural killer (NK) cells, and B cells. Cbl-b-IN-15 can activate T cell function with an EC50 of 0.41 μM.
Field of Research
Cancer Biology, Protein Biochemistry
Molecular Formula
C27H27N5O3
Storage Conditions
-20°C
Notes
For research use only.

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