Products for Research Use Only
RegisterLogin

BKT-300

CAT: 0931-T207784-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T207784-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2551033-16-8
Target
Others
Related Pathways
Others
Bioactivity
BKT-300 is a potent and selective inhibitor of Protein regulator of cytokinesis 1 (PRC1), with a Kd value of 28.3 nM. It disrupts microtubule architecture, induces G2/M phase arrest, mitotic catastrophe, and caspase-3-dependent apoptosis, presenting potential as a novel therapy for advanced acute myeloid leukemia (AML) .
Smiles
O=C1NC=2C(OC3=CC=C(O)C=C3OC)=CC(OC)=CC2C(O)=C1CCCCC
Molecular Formula
C22H25NO6
Molecular Weight
399.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

4-hydroxy-8-(4-hydroxy-2-methoxyphenoxy)-6-methoxy-3-pentyl-1H-quinolin-2-one
CAS Number2551033-16-8
PubChem CID155286998
IUPAC Name4-hydroxy-8-(4-hydroxy-2-methoxyphenoxy)-6-methoxy-3-pentyl-1H-quinolin-2-one
Molecular FormulaC22H25NO6
Molecular Weight399.4
XLogP4.2
Topological Polar Surface Area97.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Heavy Atom Count29
Formal Charge0
Complexity594
SMILES
CCCCCC1=C(C2=C(C(=CC(=C2)OC)OC3=C(C=C(C=C3)O)OC)NC1=O)O
InChI
InChI=1S/C22H25NO6/c1-4-5-6-7-15-21(25)16-11-14(27-2)12-19(20(16)23-22(15)26)29-17-9-8-13(24)10-18(17)28-3/h8-12,24H,4-7H2,1-3H3,(H2,23,25,26)
InChIKey
SOKQQBNCMIPWLR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-hydroxy-8-(4-hydroxy-2-methoxyphenoxy)-6-methoxy-3-pentyl-1H-quinolin-2-one
CAS: 2551033-16-8
CID: 155286998
Formula: C22H25NO6
MW: 399.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight399.4
XLogP34.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Exact Mass399.16818752
Monoisotopic Mass399.16818752
Topological Polar Surface Area97.3 Ų
Heavy Atom Count29
Formal Charge0
Complexity594
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T200237-01KPU-300
T88841-01TYRA-300
T85853-01BIBD-300
T35288Z 300
TP2765-01CIGB-300
T9901A-1669-01SAN-300
T22921-01LE 300
T5477-01ELQ-300
T212055-01MF-DH-300
TP3233-01CIGB-300 acetate

Alternative Products

CatalogName
E8296BKT-300
MBS3605529-01BKT-140
453061-01Polyethylene Glycol 300 (PEG 300)
BA2101-5.1ELQ-300
B6824-10LE 300
HY-P4056CIGB-300
ST853-50mlProClean 300
BUP21048-01TYRA-300
2326000CryoCenter 300
CRB1001190-01CIGB 300

Popular Products