MF-DH-300

• Target:

  Dehydrogenase

• Related Pathways:

  Metabolism

• Bioactivity:

  MF-DH-300 is a 15-PGDH inhibitor with an IC50 of 1.6 nM. It blocks the interaction between 15-PGDH and PGE2, promoting stem cell proliferation, increasing muscle strength, and enhancing mitochondrial function. Additionally, MF-DH-300 raises the expression of survival motor neuron (SMN) protein and is applicable in research on muscle diseases such as spinal muscular atrophy (SMA) .

• Smiles:

  N#CC1=CC=CC(=C1)N2C=CC=3C=C(C=NC32)C(=O)N4CCCCC4

• Molecular Formula:

  C20H18N4O

• Molecular Weight:

  330.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2673403-86-4