BKT-300

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  BKT-300 is a potent and selective inhibitor of Protein regulator of cytokinesis 1 (PRC1), with a Kd value of 28.3 nM. It disrupts microtubule architecture, induces G2/M phase arrest, mitotic catastrophe, and caspase-3-dependent apoptosis, presenting potential as a novel therapy for advanced acute myeloid leukemia (AML) .

• Smiles:

  O=C1NC=2C(OC3=CC=C(O)C=C3OC)=CC(OC)=CC2C(O)=C1CCCCC

• Molecular Formula:

  C22H25NO6

• Molecular Weight:

  399.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2551033-16-8