Products for Research Use Only
RegisterLogin

DM-4107

CAT: 0931-T207521-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T207521-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1346599-75-4
Target
P-gp
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
DM-4107 is a primary metabolite of Tolvaptan, primarily metabolized by the CYP3A4 enzyme in the liver. In SCHH cells, DM-4107 inhibits the human liver transport proteins NTCP, BSEP, MRP3, and MRP4, with IC50 values of 95.6, 119, 61.2, and 37.9 μM respectively, affecting bile acid transport. It is applicable for research on autosomal dominant polycystic kidney disease (ADPKD) .
Smiles
O=C(O)CCC(O)C1=CC(Cl)=CC=C1NC(=O)C2=CC=C(C=C2C)NC(=O)C=3C=CC=CC3C
Molecular Formula
C26H25ClN2O5
Molecular Weight
480.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T210591-01DM-4103
TSH-00009-01DM-β-CD
T68507-01DM-NOFD
T77814-01Tomaymycin DM
T62403-01DM-01
T73948-01Duocarmycin DM
T207517-01DM-4111
TMIH-0198-01DM-3411-d8
T82538-01DM-Nitrophen tertasodium
TN1663-01Ganoderic acid DM

Alternative Products

CatalogName
GTR19257696-01DM-4107
sc-69738HLA-DMβ (DM.K8)
BA4885-1DM-01
HY-165423DM-4111
HY-112068-01DM-NOFD
MBS130433Tomaymycin DM
sc-227946DM-BINAP
HY-130978-01Duocarmycin DM
GTR19248058-01DM-β-CD
ABC-TC0212DM-3

Popular Products