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Duocarmycin DM

CAT: 0931-T73948-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T73948-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ADC Cytotoxin, DNA Alkylator/Crosslinker
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
Duocarmycin DM, a toxin for antibody-drug conjugates (ADCs), functions as a DNA minor-groove alkylator. It exerts its anticancer activity through a distinct curved indole structure combined with a spirocyclopropylcyclohexadienone electrophile [1] [2].
Molecular Formula
C28H27ClF3N3O5
Molecular Weight
577.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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