Duocarmycin DM

• Target:

  ADC Cytotoxin|||DNA Alkylator/Crosslinker

• Related Pathways:

  Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Bioactivity:

  Duocarmycin DM, a toxin for antibody-drug conjugates (ADCs), functions as a DNA minor-groove alkylator. It exerts its anticancer activity through a distinct curved indole structure combined with a spirocyclopropylcyclohexadienone electrophile [1] [2].

• Molecular Formula:

  C28H27ClF3N3O5

• Molecular Weight:

  577.98

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C