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Ganoderic acid DM

CAT: 0931-TN1663-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TN1663-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
173075-45-1
Target
PARP|||Apoptosis|||Androgen Receptor|||PI3K|||CDK
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Endocrinology/Hormones|||Apoptosis
Bioactivity
Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion.
Smiles
[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@]1([H])CC3=O)[C@H](C)CC\C=C(/C)C(O)=O
Molecular Formula
C30H44O4
Molecular Weight
468.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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