Ganoderic acid DM

• Target :

  PARP|||Apoptosis|||Androgen Receptor|||PI3K|||CDK

• Related Pathways :

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Endocrinology/Hormones|||Apoptosis

• Bioactivity :

  Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion.

• Smiles :

  [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@]1([H])CC3=O)[C@H](C)CC\C=C(/C)C(O)=O

• Molecular Formula :

  C30H44O4

• Molecular Weight :

  468.67

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  173075-45-1