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DM-4107

CAT: 0013-GTR19257696-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257696-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DM-4107 is a primary metabolite of Tolvaptan, primarily metabolized by the CYP3A4 enzyme in the liver. In SCHH cells, DM-4107 inhibits the human liver transport proteins NTCP, BSEP, MRP3, and MRP4, with IC50 values of 95.6, 119, 61.2, and 37.9 μM respectively, affecting bile acid transport. It is applicable for research on autosomal dominant polycystic kidney disease (ADPKD) .
CAS Number
1346599-75-4
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C (O) CCC (O) C1=CC (Cl) =CC=C1NC (=O) C2=CC=C (C=C2C) NC (=O) C=3C=CC=CC3C
Molecular Formula
C26H25ClN2O5
Molecular Weight
480.94
Storage Conditions
-20°C
Notes
For research use only.

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