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JAK3-IN-17

CAT: 0931-T207315-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207315-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
JAK
Related Pathways
Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
JAK3-IN-17 is an orally active JAK3 inhibitor with an IC50 of 14.56 nM. It demonstrates anti-inflammatory activity by inhibiting the production of IL-2 and IL-6 in a DNCB-induced mouse model of atopic dermatitis.
Smiles
FC1=NC=CC=C1C(C=C2)=CN3C2=NC=C3C4=CC(NC(C=C)=O)=CC=C4
Molecular Formula
C21H15FN4O
Molecular Weight
358.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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