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JAK3-IN-14

CAT: 0931-T67754-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T67754-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
454234-24-3
Target
JAK, FLT
Related Pathways
JAK/STAT signaling, Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic
Purity
0.9898
Bioactivity
JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.
Smiles
C(=C1C=2C(NC1=O)=CC=C(C2)C=3C=CC=NC3)C4=CC=CN4
Molecular Formula
C18H13N3O
Molecular Weight
287.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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