JAK3-IN-9

CAT: 0931-T61814-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61814-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1430095-30-9

Target

Others, JAK

Related Pathways

Tyrosine Kinase/Adaptors, Others, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis, Stem Cells

Bioactivity

JAK3-IN-9 is a potent and orally active inhibitor of the Janus kinase 3 (JAK3) enzyme, displaying an impressive IC50 value of 1.7 nM. It exhibits high selectivity towards the JAK3 signaling pathway, making it a valuable tool for studying autoimmune diseases. Additionally, JAK3-IN-9 possesses desirable characteristics such as low toxicity and excellent oral bioavailability. It also demonstrates promising anti-arthritis activity, thus enhancing its potential as a therapeutic agent [1].

Smiles

N([C@@H](C(C)C)C)C=1C(C(N)=O)=CN=C(NC2=CC=C(OS(C)(=O)=O)C=C2)N1

Molecular Formula

C17H23N5O4S

Molecular Weight

393.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MBS5804510	JAK3-IN-9
321270-01	JAK3
abx455517-01	Tyrosine-Protein Kinase JAK3 (JAK3) Antibody
MBS6011099-01	Jak3, NT (Jak3, Tyrosine-protein kinase JAK3, Janus kinase 3)
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JAK3-IN-9

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