TDO-IN-2

• Target :

  IDO|||Indoleamine 2,3-Dioxygenase (IDO)

• Related Pathways :

  Metabolism

• Bioactivity :

  TDO-IN-2 is an orally active TDO inhibitor with an IC50 of 1.25 ?M. It exhibits antitumor activity in a Hepa1-6 liver cancer allograft mouse model. Additionally, TDO-IN-2 works synergistically with PD-1/PD-L1 inhibitor BMS-202, making it useful for studying tumor immune tolerance.

• Molecular Formula :

  C20H15N3O3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C