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LRRK2-IN-17

CAT: 0931-T207158-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207158-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2101821-86-5
Target
C-RET, LRRK2
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors, Autophagy
Bioactivity
LRRK2-IN-17 is an orally active LRRK2 inhibitor with IC50 values of 3.5 nM for WT and 3.3 nM for G2019S, and it also inhibits RET kinase with an IC50 of 59 nM. LRRK2-IN-17 is utilized in research related to cancer and Parkinson's disease (PD) .
Smiles
N(C1=C2C(=NC(NC=3N=NN(C)C3)=N1)NC=C2)[C@@H]4C=5C(CC4)=CC=CC5
Molecular Formula
C18H18N8
Molecular Weight
346.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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