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SDH-IN-25

CAT: 0931-T206959-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206959-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3052432-15-9
Target
Reactive Oxygen Species, MMP, Antifungal
Related Pathways
Microbiology/Virology, Metabolism, Proteases/Proteasome, Immunology/Inflammation, NF-κB
Bioactivity
SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.
Smiles
O=C1OC(C=2C=C(Cl)C=C(Cl)C2OCC(=O)NNC3=CC=C(Br)C=C3)CC1=C
Molecular Formula
C19H15BrCl2N2O4
Molecular Weight
486.143
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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