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BET-IN-28

CAT: 0931-T206856-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206856-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
BET-IN-28 (Compound 44) is a potent inhibitor of bromodomain and extra-terminal domain (BET) proteins, exhibiting an IC50 value of 4.47 nM for BRD4-BD1. It obstructs the interaction between BET proteins and the N-acetylated lysine residues on histone tails, leading to the downregulation of specific gene expression. BET-IN-28 is applicable in research related to hematologic malignancies and solid tumors.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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