LE 28

• Target :

  Others|||Gamma-secretase

• Related Pathways :

  Others|||Neuroscience|||Proteases/Proteasome|||Stem Cells

• Bioactivity :

  LE 28 is a selective, activity-dependent probe for legumain that fluoresces exclusively upon binding to the active enzyme. It is applicable in research on cancers and inflammatory diseases [1].

• Smiles :

  S(=O)(=O)(C1=C(C=2C3=C([O+]=C4C2C=CC(=C4)N5C=6C(CC5)=CC=CC6)C=C(C=C3)N7C=8C(CC7)=CC=CC8)C=CC=C1)N9CCC(C(NCCCNC(=O)C%10=CC(C)=C(C(OCC([C@@H](NC(=O)[C@H]%11N(C([C@@H](NC(CCCCC[N+]=%12C=%13C(C(C)(C)C%12C=CC=CC=C%14N(CC)C=%15C(C%14(C)C)=CC(S(=O)(=O)O)=CC%15)=CC(S(=O)(=O)[O-])=CC%13)=O)CCC(O)=O)=O)CCC%11)CC(O)=O)=O)=O)C(C)=C%10)=O)CC9

• Molecular Formula :

  C102H111N10O21S3

• Molecular Weight :

  1909.22

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1416080-97-1