TTT-28

• Target:

  Others|||P-gp

• Related Pathways:

  Neuroscience|||Membrane transporter/Ion channel|||Others

• Bioactivity:

  TTT-28 is a thiazole-valine peptidomimetic and a selective ABCB1 (P-gp/MDR1) inhibitor with high efficacy and low toxicity, reversing ABCB1-mediated Multidrug resistance (MDR) by selectively blocking the efflux function of ABCB1.

• Smiles:

  COc1cc(cc(OC)c1OC)C(=O)N[C@@H](C(C)C)c1nc(cs1)C(=O)Nc1ccccc1C(=O)c1ccccc1

• Molecular Formula:

  C31H31N3O6S

• Molecular Weight:

  573.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1609138-51-3