PI3K-IN-28

CAT: 0931-T73118-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T73118-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2747100-02-1

Target

Others, PI3K

Related Pathways

Others, PI3K/Akt/mTOR signaling

Bioactivity

PI3K-IN-28 is a potent PI3K inhibitor demonstrating high efficacy and lower toxicity in MCF-10a models. It exhibits half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. With a selectivity index (SI) of 39, PI3K-IN-28 emerges as a promising lead compound for the optimization of anticancer agents.

Smiles

N(/N=C/C1=CC=C(OS(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(=O)=O)C=C1)=C/2\N(C(=CS2)C3=CC=CC=C3)C4=CC=CC=C4

Molecular Formula

C26H16F9N3O3S2

Molecular Weight

653.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-178984	PI3Kα-IN-28
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PI3K-IN-28

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