STING-IN-14

• Target:

  STING

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  STING-IN-14 is a STING inhibitor with an IC50 of 0.6 nM. It effectively suppresses the activation of the IRF pathway in THP1-DualTM cells. This compound is applicable in research related to autoimmune diseases.

• Smiles:

  O=C1[C@]2(N(C3=C4C(N(N=C4)C5=C(F)C=C(F)C=C5)=NC=N3)C[C@](C2)(OC6=CC(C=7C=8C(=NN(C8)CCN9C(C(=O)NC[C@@H](C(NCC%10=CC=CC=C%10)=O)N1)COCC9)C=CC7)=CC=C6)[H])[H]

• Molecular Formula:

  C46H43F2N11O5

• Molecular Weight:

  867.901

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3070953-78-2