STING-IN-10

• Target:

  PROTACs|||STING

• Related Pathways:

  PROTAC|||Immunology/Inflammation

• Bioactivity:

  STING-IN-10 (P8) serves as both a dual degrader and inhibitor of STING, exhibiting an impressive DC50 value of 2.58 ?M in THP-1 cells. This compound also demonstrates anti-inflammatory activity.

• Smiles:

  O=C (N) C (N (C1=NC (N) =C (S1) C (=O) C2=CC=C (C=C2) S (F) (F) (F) (F) F) C3=CC=C (F) C=C3) C

• Molecular Formula:

  C35H33N7O11

• Molecular Weight:

  727.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C