Thalidomide-4-carbaldehyde

• Target :

  Ligand for E3 Ligase

• Related Pathways :

  PROTAC

• Bioactivity :

  Thalidomide-4-carbaldehyde is a thalidomide analogue that contains an aldehyde group. Thalidomide recruits E3 ligases for ubiquitination, leading to proteolysis of target proteins. The aldehyde is highly reactive with amine nucleophiles via reactions like reductive amination.

• Smiles :

  O=CC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

• Molecular Formula :

  C14H10N2O5

• Molecular Weight :

  286.24

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2369068-46-0