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PROTAC FGFR1 degrader-1

CAT: 0931-T205683-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205683-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
FGFR, PROTACs
Related Pathways
PROTAC, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
PROTAC FGFR1 degrader-1 (compound S2H) is a targeted degrader of FGFR1, demonstrating an IC50 of 26.81 nM and a DC50 of 39.78 nM in KG1a cells. This compound is composed of a CRBN-type E3 ligase ligand (blue part) Pomalidomide, a target protein ligand (red part) FGFR1ligand-1, and a PROTAC linker (black part) 9-Bromononanoic acid, together forming the conjugate E3LigaseLigand-linker Conjugate 164.
Molecular Formula
C46H54N8O8
Molecular Weight
846.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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