MI-888 TFA

CAT: 0931-T205437-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205437-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1303609-30-4
Target
MDM-2/p53
Related Pathways
Apoptosis
Bioactivity
MI-888 (TFA) is an orally active inhibitor of the MDM2-p53 interaction with a Ki of 0.44 nM. It can induce rapid, complete, and durable tumor regression in xenograft mouse models.
Smiles
C(C(O)=O)(F)(F)F.C(C(C)(C)C)[C@H]1[C@@]2([C@H]([C@H](C(N[C@H]3C[C@@](C)(O)C3)=O)N1)C4=C(F)C(Cl)=CC=C4)C=5C(NC2=O)=CC(Cl)=CC5
Molecular Formula
C30H33Cl2F4N3O5
Molecular Weight
662.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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