ABT-888

• Description:

  Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Shelf Life:

  24months