Products for Research Use Only

FK-888

CAT: 0013-GTR19240175-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19240175-01Size:100 mg
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Description
FK-888 is a selective, high affinity tachykinin NK1 receptor antagonist (Ki = 0.69 nM) that displays 320-fold selectivity for human over rat NK1 receptors. FK-888 inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo.
CAS Number
138449-07-7
Purity
0.98
Smiles
OC1CN (C (C2C3C (=CC=CC=3) N (C) C=2) =O) C (C (NC (C (N (C) CC2C=CC=CC=2) =O) CC2C=CC3C (=CC=CC=3) C=2) =O) C1
Molecular Formula
C36H36N4O4
Molecular Weight
588.69544
Notes
For research use only.

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