HDAC-IN-87

• Target:

  Antifungal|||HDAC

• Related Pathways:

  Microbiology/Virology|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Bioactivity:

  HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.

• Smiles:

  FC(F)C=1N=CN=C(OCC=2SC(=CC2)C3=NOC(=N3)C(F)(F)F)C1

• Molecular Formula:

  C13H7F5N4O2S

• Molecular Weight:

  378.277

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3039482-69-1