DI-87

CAT: 0931-T39550-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T39550-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2107280-55-5

Target

Others, DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint

Purity

0.9976

Bioactivity

DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor with good in vitro activity and low protein binding. DI-87 binds to dCK and prevents the phosphorylation of deoxycytidine by dCK, which reduces the production of dNTP and cell cycle arrest (especially in S phase) . When combined with thymidine, DI-87 significantly inhibits tumor growth.

Smiles

[C@@H](SC=1N=C(N)C=C(N)N1)(C)C=2N=C(SC2C)C3=CC(OCCN4CCOCC4)=C(OC)C=C3

Molecular Formula

C23H30N6O3S2

Molecular Weight

502.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BUP21009-01	DI-87
BUP21058-01	(S) -DI-87
BA8383-5	XMD8-87
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MBS5754654	C 87
52931-01	Tartrazine, 87%
GTR19208382-01	H-87
HY-176401	AChE-IN-87
HY-173183	α-Glucosidase-IN-87

DI-87

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