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CB1R antagonist 2

CAT: 0931-T205110-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205110-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
P38 MAPK, Cannabinoid Receptor, NF-κB
Related Pathways
MAPK, GPCR/G Protein, NF-κB
Bioactivity
CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.
Molecular Formula
C24H26N4O
Molecular Weight
386.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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